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Article

Identification and characterization of Schizosaccharomyces pombe asp1(+), a gene that interacts with mutations in the Arp2/3 complex and actin.

Genetics - 1 Jul 1999

Feoktistova A, McCollum D, Ohi R, Gould K L

Abstract excerpt

The Arp2/3 complex is an essential component of the actin cytoskeleton in yeast and is required for the movement of actin patches. In an attempt to identify proteins that interact with this complex in the fission yeast Schizosaccharomyces pombe, we sought high-copy suppressors of the S. pombe arp3-c1 mutant, and have identified one, which we have termed asp1(+). The asp1(+) open reading frame (ORF) predicts a...

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Identifiers

PMID: 10388810
DOI: 10.1093/genetics/152.3.895
PMCID: PMC1460656

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