Article
A susceptibility gene for type 2 diabetes confers substantial risk for diabetes complicating cystic fibrosis.
Diabetologia - 1 Sept 2009
Blackman S M, Hsu S, Ritter S E, Naughton K M, Wright F A, Drumm M L, Knowles M R, Cutting G R
Abstract excerpt
AIMS/HYPOTHESIS: Insulin-requiring diabetes affects 25-50% of young adults with cystic fibrosis (CF). Although the cause of diabetes in CF is unknown, recent heritability studies in CF twins and siblings indicate that genetic modifiers play a substantial role. We sought to assess whether genes conferring risk for diabetes in the general population may play a risk modifying role in CF. METHODS: We tested whether a...
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