Article
Amplification and overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma.
PloS one - 7 Jul 2009
Lu Yuan, Ryan Sarra L, Elliott David J, Bignell Graham R, Futreal P Andrew, Ellison David W, Bailey Simon, Clifford Steven C
Abstract excerpt
BACKGROUND: Medulloblastoma is the most common malignant brain tumour of childhood. The identification of critical genes involved in its pathogenesis will be central to advances in our understanding of its molecular basis, and the development of improved therapeutic approaches. METHODOLOGY/PRINCIPAL FINDINGS: We performed a SNP-array based genome-wide copy number analysis in medulloblastoma cell lines, to...
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