Article
Association between regional cerebral blood flow during hypoglycemia and genetic and phenotypic traits of the renin-angiotensin system.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Nov 2009
Bie-Olsen Lise Grimmeshave, Pedersen-Bjergaard Ulrik, Kjaer Troels Wesenberg, Lonsdale Markus Nowak, Law Ian, Thorsteinsson Birger
Abstract excerpt
The risk of severe hypoglycemia in patients with type I diabetes and high basal activity in the renin-angiotensin system (RAS) is significantly higher than in patients with low basal RAS activity. In healthy men, we tested the hypothesis that differences in spontaneous RAS activity are associated with differences in cerebral activity responses during mild hypoglycemia. A total of 10 healthy men with high and 10...
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