Article
Genetic variation and activity of the renin-angiotensin system and severe hypoglycemia in type 1 diabetes.
The American journal of medicine - 1 Mar 2008
Pedersen-Bjergaard Ulrik, Dhamrait Sukhbir S, Sethi Amar A, Frandsen Erik, Nordestgaard Børge G, Montgomery Hugh E, Pramming Stig, Hougaard Philip, Thorsteinsson Birger
Abstract excerpt
BACKGROUND: The deletion-allele of the angiotensin-converting enzyme (ACE) gene and elevated ACE activity are associated with increased risk of severe hypoglycemia in type 1 diabetes. We explored whether genetic and phenotypic variations in other components of the renin-angiotensin system are sim...
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