Vascular endothelial growth factor polymorphisms and esophageal cancer prognosis.

doi:10.1158/1078-0432.CCR-09-0192

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Article

Vascular endothelial growth factor polymorphisms and esophageal cancer prognosis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2009

Bradbury Penelope A, Zhai Rihong, Ma Clement, Xu Wei, Hopkins Jessica, Kulke Matthew J, Asomaning Kofi, Wang Zhaoxi, Su Li, Heist Rebecca S, Lynch Thomas J, Wain John C, Christiani David, Liu Geoffrey

Abstract excerpt

PURPOSE: Vascular endothelial growth factor (VEGF) promotes angiogenesis and vascular permeability. The VEGF gene is polymorphic. We investigated the prognostic significance of three VEGF single nucleotide polymorphisms (SNP) in esophageal cancer. EXPERIMENTAL DESIGN: Three hundred sixty-one patients were genotyped for three VEGF SNPs (-460T/C, 405G/C, and 936C/T) using DNA extracted from prospectively collected...

Topics

Adult
Aged
Aged, 80 and over
Esophageal Neoplasms
Female
Gene Frequency
Genotype
Haplotypes
Humans
Kaplan-Meier Estimate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Neoplasm Staging

Polymorphism, Single Nucleotide

Prognosis

Vascular Endothelial Growth Factor A

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 19584152
DOI: 10.1158/1078-0432.CCR-09-0192
PMCID: PMC2742698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19584152-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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