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Article

Discovery and validation of vascular endothelial growth factor (VEGF) pathway polymorphisms in esophageal adenocarcinoma outcome.

Carcinogenesis - 1 Sept 2015

Eng Lawson, Azad Abul Kalam, Qiu Xin, Kong Qin Quinn, Cheng Dangxiao, Ying Nanjiao, Tse Alvina, Kuang Qin, Dodbiba Lorin, Renouf Daniel J, Marsh Sharon, Savas Sevtap, Mackay Helen J, Knox Jennifer J, Darling Gail E, Wong Rebecca K S, Xu Wei, Liu Geoffrey, Faluyi Olusola O

Abstract excerpt

Polymorphisms in the vascular endothelial growth factor (VEGF)/angiogenesis pathway have been implicated previously in cancer risk, prognosis and response to therapy including in esophageal adenocarcinoma. Prior esophageal adenocarcinoma studies focused on using candidate polymorphisms, limiting the discovery of novel polymorphisms. Here, we applied the tagSNP (single nucleotide polymorphism) approach to identify...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26014353
DOI: 10.1093/carcin/bgv073

Genes

FLT1
KDR
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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