Article
Association of genetic polymorphisms in the VEGF gene with breast cancer survival.
Cancer research - 15 Jun 2005
Lu Hua, Shu Xiao-Ou, Cui Yong, Kataoka Nobuhiko, Wen Wanqing, Cai Qiuyin, Ruan Zhi-Xian, Gao Yu-Tang, Zheng Wei
Abstract excerpt
The vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis and vascular permeability. VEGF overexpression has been associated with advanced stage and poor survival of several cancers. We evaluated the association of functional polymorphisms in the VEGF gene with breast cancer survival in a cohort of 1,193 breast cancer patients who were recruited as part of a population-based...
Topics
- Adult
- Breast Neoplasms
- Case-Control Studies
- Cohort Studies
- Disease-Free Survival
- Female
- Genotype
- Humans
- Middle Aged
- Neoplasm Staging
- Polymorphism, Genetic
