Article
Investigation of vascular endothelial growth factor gene polymorphisms and its association with clinicopathologic characteristics in gastric cancer.
Oncology - 1 Jan 2006
Chae Yee Soo, Kim Jong Gwang, Sohn Sang Kyun, Cho Yoon Young, Moon Joon Ho, Bae Han-Ik, Park Jae Yong, Lee Myung-Hoon, Lee Hyun-Chul, Chung Ho Young, Yu Wansik
Abstract excerpt
OBJECTIVE: Vascular endothelial growth factor (VEGF) is known to be a potent proangiogenic factor. This study evaluates the potential association of three VEGF gene polymorphisms (-460T > C, +405G > C, and 936C > T) with the susceptibility to and clinicopathologic characteristics of gastric cancer. METHODS: The VEGF genotypes were determined using paraffin-embedded tissue from 413 patients who underwent a...
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