Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of EGF and VEGF predict prognosis of patients with advanced esophageal squamous cell carcinoma.

PloS one - 1 Jan 2014

Yang Pei-Wen, Hsieh Min-Shu, Huang Ya-Chuan, Hsieh Ching-Yueh, Chiang Tzu-Hsuan, Lee Jang-Ming

Abstract excerpt

PURPOSE: To investigate the association between genetic polymorphisms of growth factor-related genes and prognosis in patients with advanced esophageal squamous cell carcinoma (ESCC). PATIENTS AND METHODS: A total of 334 ESCC patients with advanced tumor stages (stages IIB, III and IV) were enrolled in the study. The genotypes of 14 candidate single nucleotide polymorphisms (SNPs) involved in growth...

Topics

Aged
Carcinoma, Squamous Cell
Disease-Free Survival
Epidermal Growth Factor
Esophageal Neoplasms
Esophageal Squamous Cell Carcinoma
Female
Genetic Predisposition to Disease
Humans
Kaplan-Meier Estimate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Multivariate Analysis

Neoplasm Recurrence, Local

Neoplasm Staging

Polymorphism, Single Nucleotide

Prognosis

Vascular Endothelial Growth Factor A

Source

Open in PubMed Open full text

Identifiers

PMID: 24945674
DOI: 10.1371/journal.pone.0100326
PMCID: PMC4063891

Genes

EGF
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of EGF and VEGF predict prognosis of patients with advanced esophageal squamous cell carcinoma.PMID 24945674Read ↗

Polymorphisms of insulin-like growth factor binding protein-3 as a predictor for risk and patient survival in esophageal squamous cell carcinoma.Semantic proximity Read ↗

Discovery and validation of vascular endothelial growth factor (VEGF) pathway polymorphisms in esophageal adenocarcinoma outcome.Semantic proximity Read ↗

Vascular endothelial growth factor polymorphisms and esophageal cancer prognosis.Semantic proximity Read ↗

PIK3CA mutation is a favorable prognostic factor in esophageal cancer: molecular profile by next-generation sequencing using surgically resected formalin-fixed, paraffin-embedded tissue.Semantic proximity Read ↗

Effect of vascular endothelial growth factor rs35569394 in esophageal cancer and response to chemotherapy.Semantic proximity Read ↗

A functional epidermal growth factor (EGF) polymorphism, EGF serum levels, and esophageal adenocarcinoma risk and outcome.Semantic proximity Read ↗

A genetic variant in CDKN2A/2B locus was associated with poor prognosis in patients with esophageal squamous cell carcinomaSemantic proximity Read ↗

A functional polymorphism in the epidermal growth factor gene predicts hepatocellular carcinoma risk in Japanese hepatitis C patientsSemantic proximity Read ↗

Genetic variants in epidermal growth factor receptor pathway genes and risk of esophageal squamous cell carcinoma and gastric cancer in a Chinese population.Semantic proximity Read ↗

Meta-analysis of epidermal growth factor polymorphisms and cancer risk: involving 9,779 cases and 15,932 controls.Semantic proximity Read ↗

Association between epidermal growth factor polymorphism and esophageal squamous cell carcinoma susceptibility.Semantic proximity Read ↗

Association of VEGF Gene Polymorphisms with the Risk and Prognosis of Cutaneous Squamous Cell Carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.