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Article

Molecular diagnosis of myeloproliferative neoplasms.

Expert review of molecular diagnostics - 1 Jul 2009

Patnaik Mrinal M, Tefferi Ayalew

Abstract excerpt

The molecular profiling of myeloproliferative neoplasms (MPNs) has introduced a paradigm shift in the process of diagnosis, prognostication, monitoring and treatment of these diseases. The discovery of the BCR-ABL fusion oncogene is an example of a remarkable bench-to-bedside story. It has provided a comprehensive explanation of the pathogenesis of chronic myelogenous leukemia, and has resulted in the development...

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Topics

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Share to Fusion Proteins, bcr-abl
Share to In Situ Hybridization, Fluorescence
Share to Karyotyping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Molecular Diagnostic Techniques

Share to Myeloproliferative Disorders

Share to Neoplasm Proteins

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Source

Identifiers

PMID: 19580432
DOI: 10.1586/erm.09.29

Genes

BCR
JAK2
MPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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