Sequential transmission and long-term persistence of an HIV strain partially resistant to protease inhibitors.

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Article

Sequential transmission and long-term persistence of an HIV strain partially resistant to protease inhibitors.

The new microbiologica - 1 Apr 2009

Polilli Ennio, Di Masi Francesco, Sozio Federica, Mazzotta Elena, Alterio Luciana, Cosentino Luana, Clerico Luigi, Perno Carlo Federico, Parruti Giustino

Abstract excerpt

Transmission of drug-resistant HIV-1 variants has been increasingly documented. The most commonly observed resistance-associated mutations are thymidine analogue mutations as well as non-nucleoside reverse transcriptase inhibitor mutations. We report on a case of secondary transmission of a protease inhibitor (PI) primary mutation from an infected untreated subject to his sexual partner. Sequences isolated from...

Topics

Adult
Amino Acid Substitution
Drug Resistance, Viral
Female
Genetic Variation
HIV Infections
HIV-1
Humans
Male
Protease Inhibitors
RNA, Viral
Romania
Viremia

Source

Open in PubMed

Identifiers

PMID: 19579701

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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