Article
Polymorphisms of the interferon gamma and interleukin 10 genes in human brucellosis.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Dec 2003
Bravo M J, de Dios Colmenero J, Alonso A, Caballero A
Abstract excerpt
We genotyped 83 patients with brucellosis and 101 controls to determine the influence of polymorphisms of the interferon gamma (IFNG) and interleukin 10 (IL10) genes on protection against, or susceptibility to, human brucellosis and its complications. The results showed a significant increase in the IFNG +874A/A genotype in patients compared with controls (34% vs. 19%) (P = 0.023, odds ratio = 2.17, 95%...
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