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Article

COMT gene Val158Met polymorphism influences the severity of intestinal metaplasia in H. pylori infected older subjects.

Hepato-gastroenterology - 1 Jan 2000

Tahara Tomomitsu, Shibata Tomoyuki, Nakamura Masakatsu, Yoshioka Daisuke, Okubo Masaaki, Maruyama Naoko, Kamano Toshiaki, Kamiya Yoshio, Fujita Hiroshi, Nagasaka Mitsuo, Iwata Masami, Takahama Kazuya, Watanabe Makoto, Yamashita Hiromi, Nakano Hiroshi, Hirata Ichiro, Arisawa Tomiyasu

Abstract excerpt

BACKGROUND/AIMS: A complex interaction of host genetic and environmental factors may be relevant in the development of Helocobacter pylori (H. pylori) related gastroduodenal diseases. Catechol-O-methyltransferase (COMT) is expressed catalyzes the methylation of various endobiotic and xenobiotic substances and thus might protect DNA from oxidative damage. We aimed to clarify the effect of COMT functional...

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Source

Identifiers

PMID: 19579610

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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