Article
The AP-1 transcription factor Batf controls T(H)17 differentiation.
Nature - 16 Jul 2009
Schraml Barbara U, Hildner Kai, Ise Wataru, Lee Wan-Ling, Smith Whitney A-E, Solomon Ben, Sahota Gurmukh, Sim Julia, Mukasa Ryuta, Cemerski Saso, Hatton Robin D, Stormo Gary D, Weaver Casey T, Russell John H, Murphy Theresa L, Murphy Kenneth M
Abstract excerpt
Activator protein 1 (AP-1, also known as JUN) transcription factors are dimers of JUN, FOS, MAF and activating transcription factor (ATF) family proteins characterized by basic region and leucine zipper domains. Many AP-1 proteins contain defined transcriptional activation domains, but BATF and the closely related BATF3 (refs 2, 3) contain only a basic region and leucine zipper, and are considered to be...
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