Article
Crystal structure and assembly of the functional Nanoarchaeum equitans tRNA splicing endonuclease.
Nucleic acids research - 1 Sept 2009
Mitchell Michelle, Xue Song, Erdman Rachel, Randau Lennart, Söll Dieter, Li Hong
Abstract excerpt
The RNA splicing and processing endonuclease from Nanoarchaeum equitans (NEQ) belongs to the recently identified (alphabeta)(2) family of splicing endonucleases that require two different subunits for splicing activity. N. equitans splicing endonuclease comprises the catalytic subunit (NEQ205) and the structural subunit (NEQ261). Here, we report the crystal structure of the functional NEQ enzyme at 2.1 A...
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