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Article

Variations of ABCB4 and ABCB11 genes are associated with primary intrahepatic stones.

Molecular medicine reports - 1 Jan 2015

Pan Shuguang, Li Xiaowu, Jiang Peng, Jiang Yan, Shuai Ling, He Yu, Li Zhihua

Abstract excerpt

Variations of the ABCB4 and ABCB11 genes affect the composition of bile and are associated with cholestasis and cholelithiasis. However, their roles in the formation of primary intrahepatic stones (PIS) remains to be elucidated. The aim of the present study was to determine whether there is an association between PIS and variations in these genes. Exon sequencing was performed in order to analyze the ABCB4 and...

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Source

Identifiers

PMID: 25323205
DOI: 10.3892/mmr.2014.2645

Genes

ABCB11
ABCB4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Variations of ABCB4 and ABCB11 genes are associated with primary intrahepatic stones.PMID 25323205Read ↗

Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11Semantic proximity Read ↗

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The role of genetic mutations in intrahepatic cholestasis of pregnancySemantic proximity Read ↗

An expanded role for heterozygous mutations of ABCB4, ABCB11, ATP8B1, ABCC2 and TJP2 in intrahepatic cholestasis of pregnancySemantic proximity Read ↗

Common ABCB4 and ABCB11 Genotypes Are Associated with Idiopathic Chronic Cholestasis in Adults.Semantic proximity Read ↗

Compound heterozygous mutations of ABCB11 responsible for benign recurrent intrahepatic cholestasis.Semantic proximity Read ↗

Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy.Semantic proximity Read ↗

[Research on the relationship between V444A mutation of ABCB11 gene and primary intrahepatic stone].Semantic proximity Read ↗

ATP8B1, ABCB11, and ABCB4 Genes Defects: Novel Mutations Associated with Cholestasis with Different Phenotypes and Outcomes.Semantic proximity Read ↗

Common variants of ABCB4 and ABCB11 and plasma lipid levels: a study in sib pairs with gallstones, and controls.Semantic proximity Read ↗

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