Article
Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organisation during neuronal growth.
Journal of cell science - 15 Jul 2009
Sanchez-Soriano Natalia, Travis Mark, Dajas-Bailador Federico, Gonçalves-Pimentel Catarina, Whitmarsh Alan J, Prokop Andreas
Abstract excerpt
Spectraplakins are large actin-microtubule linker molecules implicated in various processes, including gastrulation, wound healing, skin blistering and neuronal degeneration. Expression data for the mammalian spectraplakin ACF7 and genetic analyses of the Drosophila spectraplakin Short stop (Shot) suggest an important role during neurogenesis. Using three parallel neuronal culture systems we demonstrate that,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
