Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients.

International journal of cancer - 1 Oct 2009

Zhou Jia, Ding Tong, Pan Weidong, Zhu Ling-Yan, Li Lian, Zheng Limin

Abstract excerpt

Immunosuppression mediated by regulatory T cells (Tregs) is a key facilitator of tumor immune evasion, but the source of these Tregs and their contribution to human cancer progression remains unclear. This study investigated the properties of FoxP3(+) Tregs, their prognostic value in patients with hepatocellular carcinoma (HCC) and the underlying mechanisms of FoxP3(+) Treg intratumoral accumulation. In addition...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Transcription Factors

Share to Liver Neoplasms

Share to Macrophages

Share to Microscopy, Confocal

Share to Proportional Hazards Models

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 19569243
DOI: 10.1002/ijc.24556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients.PMID 19569243Read ↗

Progression on the Roles and Mechanisms of Tumor-Infiltrating T Lymphocytes in Patients With Hepatocellular Carcinoma.Semantic proximity Read ↗

FOXP3+ Treg as a therapeutic target for promoting anti-tumor immunity.Semantic proximity Read ↗

Roles of CD4+CD25(high) FOXP3+ Tregs in lymphomas and tumors are complex.Semantic proximity Read ↗

FOXP3+ Tregs: heterogeneous phenotypes and conflicting impacts on survival outcomes in patients with colorectal cancer.Semantic proximity Read ↗

IL-2 availability regulates the tissue specific phenotype of murine intra-hepatic Tregs.Semantic proximity Read ↗

Epigenetic control of Foxp3 in intratumoral T-cells regulates growth of hepatocellular carcinomaSemantic proximity Read ↗

Prognostic value of peripheral and local forkhead box P3+ regulatory T cells in patients with non-small-cell lung cancerSemantic proximity Read ↗

CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo.Semantic proximity Read ↗

Both CD8+ and CD4+ T regulatory cells are associated with poor survival in colorectal cancerSemantic proximity Read ↗

Prognostic Role of Immune Cells in Hepatitis B-associated Hepatocellular Carcinoma Following Surgical Resection Depends on Their Localization and Tumor Size.Semantic proximity Read ↗

The distribution of intratumoral macrophages correlates with molecular phenotypes and impacts prognosis in colorectal carcinoma.Semantic proximity Read ↗

FOXP3+ T regulatory lymphocytes in primary melanoma are associated with BRAF mutation but not with response to BRAF inhibitor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.