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Article

MRP2 and GSTP1 polymorphisms and chemotherapy response in advanced non-small cell lung cancer.

Cancer chemotherapy and pharmacology - 1 Feb 2010

Sun Ning, Sun Xinchen, Chen Baoan, Cheng Hongyan, Feng Jifeng, Cheng Lu, Lu Zuhong

Abstract excerpt

PURPOSE: The level of drug metabolism and drug transport is correlated with the sensitivity of cancer cells towards platinum-based chemotherapy. We hypothesize that genetic polymorphisms in metabolising enzymes gene GSTP1 (glutathione S-transferase P1), and MRP2 (multidrug resistance-associated protein 2) (ABCC2), which result in inter-individual differences in metabolism and drug disposition, may predict...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19568750
DOI: 10.1007/s00280-009-1046-1
PMCID: PMC2797421

Genes

GSTP1
ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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