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Article

Polymorphisms in XRCC1 and XPG and response to platinum-based chemotherapy in advanced non-small cell lung cancer patients.

Lung cancer (Amsterdam, Netherlands) - 1 Aug 2009

Sun Xinchen, Li Fan, Sun Ning, Shukui Qin, Baoan Chen, Jifeng Feng, Lu Cheng, Zuhong Lu, Hongyan Cheng, YuanDong Cao, Jiazhong Ji, Yingfeng Zhou

Abstract excerpt

Platinum-based chemotherapeutics is the most common regimens for advanced NSCLC patients. However, it is difficult to identify platinum resistance in clinical treatment. Genetic factors are thought to represent important determinants of drug efficacy. In this study, we investigated whether single nucleotide polymorphisms (SNPs) in Xeroderma pigmentosum group G (XPG) and X-ray repair cross complementing group 1...

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Source

Identifiers

PMID: 19157633
DOI: 10.1016/j.lungcan.2008.11.014

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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