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Article

Lack of association of TIM3 polymorphisms and allergic phenotypes.

BMC medical genetics - 30 Jun 2009

Zhang Jian, Daley Denise, Akhabir Loubna, Stefanowicz Dorota, Chan-Yeung Moira, Becker Allan B, Laprise Catherine, Paré Peter D, Sandford Andrew J

Abstract excerpt

BACKGROUND: T-cell immunoglobulin mucin-3 (TIM3) is a TH1-specific type 1 membrane protein that regulates TH1 proliferation and the development of immunological tolerance. TIM3 and its genetic variants have been suggested to play a role in regulating allergic diseases. Polymorphisms in the TIM3 promoter region have been reported to be associated with allergic phenotypes in several populations. The aims of this...

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Identifiers

PMID: 19566956
DOI: 10.1186/1471-2350-10-62
PMCID: PMC2711936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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