Article
Genetic variants of the T-cell immunoglobulin mucin 1 but not the T-cell immunoglobulin mucin 3 gene are associated with asthma in an African American population.
The Journal of allergy and clinical immunology - 1 May 2005
Gao Pei-Song, Mathias Rasika A, Plunkett Beverly, Togias Alkis, Barnes Kathleen C, Beaty Terri H, Huang Shau-Ku
Abstract excerpt
BACKGROUND: The T-cell immunoglobulin mucin ( TIM ) proteins and their genetic variants have been suggested to play a role in regulating allergic diseases. OBJECTIVE: Genetic association of the sequence variants for TIM-1 and TIM-3 genes with asthma in an African American population was investigated. METHODS: Both case-control and family-based association analyses were performed for a total of 7 polymorphisms,...
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