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Article

The association of TIM-3 gene polymorphism with atopic disease in Korean population.

Human immunology - 1 Dec 2004

Chae Soo-Cheon, Park Young-Ran, Lee Yong-Chul, Lee Jae-Hoon, Chung Hun-Taeg

Abstract excerpt

The family of T-cell immunoglobulin domain and mucin domain (TIM) proteins is identified to be expressed on T cells. A member of the TIM family, TIM-3 is selectively expressed on the surface of differentiated T helper 1 (Th1) cells. TIM-3 might have an important role in the induction of autoimmune diseases by regulating macrophage activation and interacts with the TIM-3 ligand to regulate Th1 responses. In the...

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Source

Identifiers

PMID: 15603868
DOI: 10.1016/j.humimm.2004.07.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The association of TIM-3 gene polymorphism with atopic disease in Korean population.PMID 15603868Read ↗

Molecular variations in Th1-specific cell surface gene Tim-3.Semantic proximity Read ↗

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The polymorphisms of Th1 cell surface gene Tim-3 are associated in a Korean population with rheumatoid arthritis.Semantic proximity Read ↗

The association of the exon 4 variations of Tim-1 gene with allergic diseases in a Korean population.Semantic proximity Read ↗

Association between Gene Polymorphisms of T Cell Immunoglobulin Domain and Mucin Domain-3 and Risk of Asthma: A Systematic Review and Meta-analysis.Semantic proximity Read ↗

Association between TIM-1 gene polymorphisms and allergic rhinitis in a Han Chinese population.Semantic proximity Read ↗

T cell immunoglobulin- and mucin-domain-containing molecule 3 gene polymorphisms and susceptibility to pancreatic cancer.Semantic proximity Read ↗

Family-based association study of Tim-1 and Tim-3 gene polymorphisms with childhood asthma in Chinese trios.Semantic proximity Read ↗

TIM-3 rs1036199 polymorphism increases susceptibility to autoimmune diseases: evidence based on 4200 subjectsSemantic proximity Read ↗

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Molecular variations in the promoter and coding regions of human Tim-1 gene and their association in Koreans with asthma.Semantic proximity Read ↗

Genetic variants of the T-cell immunoglobulin mucin 1 but not the T-cell immunoglobulin mucin 3 gene are associated with asthma in an African American population.Semantic proximity Read ↗

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