Familial incidence of C3 nephritic factor.

doi:10.1159/000186562

Article

Familial incidence of C3 nephritic factor.

Nephron - 1 Jan 1991

López-Trascasa M, Martín-Villa J M, Vicario J L, Marín M A, Martínez-Ara J, García-Messeguer M C, Arnáiz-Villena A, Fontán G

Abstract excerpt

C3 nephritic factor (NEF) has been found in 3 siblings presenting different (or none) degrees of renal disease. Other relatives, including their dead father, suffered from a renal illness. In 2 of the siblings, NEF activity was restricted to IgG1 and IgG3 subclasses. Familial NEF incidence and a...

Topics

Adolescent
Adult
Complement C3
Complement C3 Nephritic Factor
Complement C4
Female
Glomerulonephritis
HLA Antigens
Humans
Immunoglobulin G
Male
Middle Aged
Phenotype

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