Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population Pharmacokinetics of Linezolid in Adults with Pulmonary Tuberculosis

30 Jun 2009

Abstract excerpt

Nineteen adults with pulmonary tuberculosis received linezolid (600 mg) once or twice daily in an early bactericidal activity trial. A one-compartment population model produced median values for the absorption rate constant, volume of distribution, and elimination rate constant of 1.5 h(-1), 29.6 liters, and 0.25 h(-1) (once daily) and 2.7 h(-1), 32.1 liters, and 0.15 h(-1) (twice daily). Linezolid administered...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Infectious Diseases and Tuberculosis
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19564361
DOI: 10.1128/aac.01378-08

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population Pharmacokinetics of Linezolid in Adults with Pulmonary TuberculosisPMID 19564361Read ↗

Population pharmacokinetics and dose evaluations of linezolid in the treatment of multidrug-resistant tuberculosisSemantic proximity Read ↗

Use of an in vitro pharmacodynamic model to derive a linezolid regimen that optimizes bacterial kill and prevents emergence of resistance in Bacillus anthracis.Semantic proximity Read ↗

Population Pharmacokinetics and Pharmacogenetics of Ethambutol in Adult Patients Coinfected with Tuberculosis and HIV.Semantic proximity Read ↗

A population approach of rifampicin pharmacogenetics and pharmacokinetics in Mexican patients with tuberculosis.Semantic proximity Read ↗

Population pharmacokinetic model of isoniazid in patients with tuberculosis in Tunisia.Semantic proximity Read ↗

Clinical Population Pharmacokinetics and Toxicodynamics of LinezolidSemantic proximity Read ↗

Pharmacokinetics of anti-tuberculosis drugs in children.Semantic proximity Read ↗

Population Pharmacokinetic Modeling of Bedaquiline among Multidrug-Resistant Pulmonary Tuberculosis Patients from China.Semantic proximity Read ↗

Rifampicin population pharmacokinetics and pharmacogenomic evaluation of SLCO1B1 gene in tuberculosis patients.Semantic proximity Read ↗

PHARMACOKINETIC STUDY OF BEDAQUILINE AMONG INDIAN MDR-TB PATIENTS IN CLINICAL SETTINGSSemantic proximity Read ↗

Development of population pharmacokinetics model of isoniazid in Indonesian patients with tuberculosis.Semantic proximity Read ↗

N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in patients with drug-resistant pulmonary tuberculosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.