Article
Impact of genetic variations of the CYP1A1, GSTT1, and GSTM1 genes on the risk of coronary artery disease.
DNA and cell biology - 1 Feb 2012
Taspinar Mehmet, Aydos Sena, Sakiragaoglu Onur, Duzen Irfan Veysel, Yalcinkaya Adnan, Oztuna Derya, Bardakci Hasmet, Tutar Eralp, Sunguroglu Asuman
Abstract excerpt
Carcinogenic and toxic molecules produce DNA adducts that contribute to the development of atherosclerosis. Genetic polymorphisms of xenobiotic-detoxified enzymes, which control the level of DNA adducts, may affect both enzymatic activity and individual susceptibility to coronary artery disease (...
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