Article
[Association of the MspI polymorphism of cytochrome P4501A1 gene and smoking to the susceptibility to coronary artery disease].
Zhonghua xin xue guan bing za zhi - 1 Jun 2007
Zhang Xiao-ming, Xu Geng, Shan Jiang, Jin Guo-dong, Huang Cheng-lin, Wu Kang-song
Abstract excerpt
OBJECTIVE: To investigate the association of MspI polymorphism of Cytochrome P4501A1 (CYP1A1) gene and smoking to the susceptibility to coronary artery disease (CAD). METHODS: The genotypes of CYP1A1 MspI site were detected using the methods of polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) in 349 cases with CAD and 404 non-CAD as controls. CAD diagnosis was confirmed by coronary...
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