Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vascular smooth muscle cells as a valvular interstitial cell surrogate in heart valve tissue engineering.

Tissue engineering. Part A - 1 Dec 2009

Appleton Andrew J E, Appleton C Thomas G, Boughner Derek R, Rogers Kem A

Abstract excerpt

BACKGROUND: Vascular smooth muscle cells (VSMCs) are a potential autologous cell source for aortic valve tissue engineering, but have a phenotype that differs from that of valvular interstitial cells in vivo. We hypothesized that combining basic fibroblast growth factor (bFGF), epidermal growth f...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Count
Share to Cell Culture Techniques
Share to Extracellular Matrix

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Valves

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Tissue Engineering

Source

Identifiers

PMID: 19563261
DOI: 10.1089/ten.TEA.2009.0031

Genes

EGF
TEF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19563261-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vascular smooth muscle cells as a valvular interstitial cell surrogate in heart valve tissue engineering.PMID 19563261Read ↗

Transforming growth factor-beta1 modulates extracellular matrix production, proliferation, and apoptosis of endothelial progenitor cells in tissue-engineering scaffolds.Semantic proximity Read ↗

Porcine and human aortic valve endothelial and interstitial cell isolation and characterizationSemantic proximity Read ↗

Generation and Characterization of Human Mesenchymal Stem Cell-Derived Smooth Muscle CellsSemantic proximity Read ↗

Engineering vascular tissue with functional smooth muscle cells derived from human iPS cells and nanofibrous scaffolds.Semantic proximity Read ↗

Human Aortic Valve Interstitial Cells Display Proangiogenic Properties During Calcific Aortic Valve Disease.Semantic proximity Read ↗

The role of valvular endothelial cell paracrine signaling and matrix elasticity on valvular interstitial cell activation.Semantic proximity Read ↗

Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: distinct responses to stimuli.Semantic proximity Read ↗

Modulation of Smooth Muscle Cell Phenotype for Translation of Tissue-Engineered Vascular Grafts.Semantic proximity Read ↗

Radial artery as an autologous cell source for valvular tissue engineering efforts.Semantic proximity Read ↗

Low concentrations of TNF-α in vitro transform the phenotype of vascular smooth muscle cells and enhance their survival in a three-dimensional culture system.Semantic proximity Read ↗

Simulation of early calcific aortic valve disease in a 3D platform: A role for myofibroblast differentiation.Semantic proximity Read ↗

Porcine aortic valve interstitial cells in three-dimensional culture: comparison of phenotype with aortic smooth muscle cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.