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Article

Vascular smooth muscle cells as a valvular interstitial cell surrogate in heart valve tissue engineering.

Tissue engineering. Part A - 1 Dec 2009

Appleton Andrew J E, Appleton C Thomas G, Boughner Derek R, Rogers Kem A

Abstract excerpt

BACKGROUND: Vascular smooth muscle cells (VSMCs) are a potential autologous cell source for aortic valve tissue engineering, but have a phenotype that differs from that of valvular interstitial cells in vivo. We hypothesized that combining basic fibroblast growth factor (bFGF), epidermal growth factor (EGF), or platelet-derived growth factor (PDGF) with transforming growth factor beta-1 (TGF-beta1) would achieve...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19563261
DOI: 10.1089/ten.TEA.2009.0031

Genes

EGF
TEF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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