Article
Preferential expression of phosphatidylglucoside along neutrophil differentiation pathway.
Leukemia & lymphoma - 1 Jul 2009
Oka Satoko, Nagatsuka Yasuko, Kikuchi Jiro, Yokote Taiji, Hirabayashi Yoshio, Hanafusa Toshiaki, Ozawa Keiya, Muroi Kazuo
Abstract excerpt
Phosphatidylglucoside (PtdGlc), a new type of glycolipid, was recently identified. We examined PtdGlc expression in normal blood cells and leukemic cells using an anti-PtdGlc monoclonal antibody, DIM-21. Neutrophils, monocytes, HL-60 cells and a subset of cord blood (CB) CD34(+) cells, but not erythroblasts, expressed lipid antigen. PtdGlc was preferentially expressed along the neutrophil differentiation pathway...
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