Article
Survivin as a target for new anticancer interventions.
Journal of cellular and molecular medicine - 1 Jan 2000
Zaffaroni Nadia, Pennati Marzia, Daidone Maria Grazia
Abstract excerpt
Survivin is a member of the inhibitor of apoptosis protein (IAP) family, that has been implicated in both control of cell division and inhibition of apoptosis. Specifically, its anti-apoptotic function seems to be related to the ability to directly or indirectly inhibit caspases. Survivin is selectively expressed in the most common human neoplasms and appears to be involved in tumor cell resistance to some...
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