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Article

The Role of Survivin for Radiation Oncology: Moving Beyond Apoptosis Inhibition

1 Jan 2011

Abstract excerpt

Alterations in the expression of apoptosis-related proteins, like the inhibitor of apoptosis (IAP) protein family, display a pivotal pathway by which cancer cells acquire resistance to therapeutic treatment. Among this family, survivin, the smallest and structural unique member, deserves growing attention due to its universal over-expression in human tumors, and its prominent role in disparate networks of...

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PMID: 21110807
DOI: 10.2174/092986711794088362

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