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Article

High prevalence and fixation of Plasmodium vivax dhfr/dhps mutations related to sulfadoxine/pyrimethamine resistance in French Guiana.

The American journal of tropical medicine and hygiene - 1 Jul 2009

Barnadas Céline, Musset Lise, Legrand Eric, Tichit Magali, Briolant Sébastien, Fusai Thierry, Rogier Christophe, Bouchier Christiane, Picot Stéphane, Ménard Didier

Abstract excerpt

Plasmodium vivax isolates from French Guiana were studied for the presence of mutations associated with sulfadoxine/pyrimethamine (SP) drug resistance. Ninety-six blood samples were collected from 2000 to 2005 from symptomatic malaria patients. SP drug resistance was predicted by determining point mutations in the dihydrofolate reductase (pvdhfr) and dihydropteroate synthase (pvdhps) genes. All samples showed...

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PMID: 19556560

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