Article
Association of thymic stromal lymphopoietin gene -847C>T polymorphism in generalized vitiligo.
Experimental dermatology - 1 Dec 2009
Cheong Kyung Ah, Chae Soo-Cheon, Kim Yong-Shin, Kwon Hyok Bu, Chung Hun-Taeg, Lee Ai-Young
Abstract excerpt
Thymic stromal lymphopoietin (TSLP) induces naïve CD4+ T cells to produce Th2 cytokines. In addition, to low production of Th2 cytokines, strong Th1 response, which plays an important role in vitiligo development, has been induced by blockade of TSLP or TSLP receptor. This study examined whether a functional TSLP polymorphism was associated with vitiligo. One hundred and sixty Korean patients with vitiligo and...
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