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Article

Efficacy of CLT4A variants as immunoregulatory molecules among Vitiligo patients in Saudi Arabia.

Scientific reports - 5 Feb 2025

Alshammary Amal F, BinSaif Ghada, Ali Khan Imran

Abstract excerpt

Vitiligo is a skin depigmentation condition caused by the immune-mediated perdition of melanocytes. In vitiligo, cytotoxic T-lymphocytes damage melanocytes, causing skin depigmentation. The Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) gene has been reported to be related to vitiligo and other autoimmune diseases. The purpose of this study was to explore the molecular involvement of rs231775 and rs3087243 SNPs in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39910232
DOI: 10.1038/s41598-025-88749-z
PMCID: PMC11799352

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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