Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-21 rs2055979 and serum IL-21 levels are associated with both non-segmental and segmental vitiligo in an Iranian cohort.

BMC immunology - 18 May 2026

Gholijani Nasser, Dehghan Zeinab, Abolmaali Samira Sadat, Talepoor Atefe Ghamar, Yazdani Mohammadreza, Daryabor Gholamreza

Abstract excerpt

BACKGROUND: Vitiligo is an autoimmune disorder primarily categorized into non-segmental (NSV) and segmental (SV) subtypes. Interleukin-21 (IL-21) is a pleiotropic cytokine implicated in immune dysregulation. OBJECTIVE: To investigate the association of serum IL-21 levels and two genetic variants (rs2055979 and rs4833837) with susceptibility to NSV and SV in an Iranian cohort. METHODS: The study included 264...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies
Share to Cohort Studies
Share to Genetic Association Studies
Share to Interleukin-21
Share to Interleukins
Share to Iran
Share to Vitiligo
Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 42144579
DOI: 10.1186/s12865-026-00846-4
PMCID: PMC13374329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-21 rs2055979 and serum IL-21 levels are associated with both non-segmental and segmental vitiligo in an Iranian cohort.PMID 42144579Read ↗

Lack of association of IL-10 (rs1800896) and IL-13 (rs1800925) with non-segmental vitiligo susceptibility in South Indian population.Semantic proximity Read ↗

Association analysis revealed one susceptibility locus for vitiligo with immune-related diseases in the Chinese Han population.Semantic proximity Read ↗

Association of rs4711998 of IL-17A, rs2275913 of IL-17A and rs763780 IL-17F gene polymorphisms with non-segmental vitiligo in a Mexican population.Semantic proximity Read ↗

Integrative Analysis to Identify Diagnostic Biomarkers (HSP90AA1, VCAM1 and MX1) and Reveal Immune Cell Infiltration Changes in Patients with VitiligoSemantic proximity Read ↗

Exploring the role of Interleukin-16 genetic variation and expression in vitiligo.Semantic proximity Read ↗

The Role of REL and IL2 and Their Polymorphisms in the Pathogenesis of Vitiligo-Exploratory Genetic Association Study.Semantic proximity Read ↗

Investigation of the Role of Interleukin 6 in Vitiligo Pathogenesis.Semantic proximity Read ↗

The changes of gene expression profiling between segmental vitiligo, generalized vitiligo and healthy individual.Semantic proximity Read ↗

An in-depth analysis identifies two new independent signals in 11q23.3 associated with vitiligo in the Chinese Han population.Semantic proximity Read ↗

Association of rs4711998 of IL-17A, rs2275913 of IL-17A and rs763780 IL-17F gene polymorphisms with vitiligo in a Mexican populationSemantic proximity Read ↗

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.Semantic proximity Read ↗

Clinical profiles of vitiligo in China: an analysis of 3742 patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.