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Article

Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics.

Molecular biology of the cell - 1 Aug 2009

Fong Ka-Wing, Hau Shiu-Yeung, Kho Yik-Shing, Jia Yue, He Lisheng, Qi Robert Z

Abstract excerpt

Mutations in cdk5rap2 are linked to autosomal recessive primary microcephaly, and attention has been paid to its function at centrosomes. In this report, we demonstrate that CDK5RAP2 localizes to microtubules and concentrates at the distal tips in addition to centrosomal localization. CDK5RAP2 in...

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Identifiers

PMID: 19553473
DOI: 10.1091/mbc.e09-01-0009
PMCID: PMC2777926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19553473-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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