The mechanisms underlying MMR deficiency in immunodeficiency-related non-Hodgkin lymphomas are different from those in other sporadic microsatellite instable neoplasms.

doi:10.1002/ijc.24681

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Article

The mechanisms underlying MMR deficiency in immunodeficiency-related non-Hodgkin lymphomas are different from those in other sporadic microsatellite instable neoplasms.

International journal of cancer - 15 Nov 2009

Borie Claire, Colas Chrystelle, Dartigues Peggy, Lazure Thierry, Rince Patricia, Buhard Olivier, Folliot Patrick, Chalastanis Alexandra, Muleris Martine, Hamelin Richard, Mercier Dominique, Oliveira Carla, Seruca Raquel, Chadburn Amy, Leblond Véronique, Barete Stéphane, Gaïdano Gianluca, Martin Antoine, Gaulard Philippe, Fléjou Jean-François, Raphael Martine, Duval Alex

Abstract excerpt

The spectrum of tumors showing microsatellite instability (MSI) has recently been enlarged to sporadic neoplasms whose incidence is favored in the context of chronic immunosuppression. We investigated the biological, therapeutic and clinical features associated with MSI in immunodeficiency-related non-Hodgkin lymphomas (ID-RL). MSI screening was performed in 275 ID-RL. MSI ID-RL were further analyzed for MMR gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mismatch Repair

Share to Immunologic Deficiency Syndromes

Share to Lymphoma, Non-Hodgkin

Share to Mismatch Repair Endonuclease PMS2

Share to MutL Protein Homolog 1

Share to MutS Homolog 2 Protein

Share to O(6)-Methylguanine-DNA Methyltransferase

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Identifiers

PMID: 19551857
DOI: 10.1002/ijc.24681

Genes

BRAF
MGMT
MLH1
KRAS
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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