Article
Sex steroidal targets & genetic susceptibility to idiopathic cryptorchidism.
Pediatric endocrinology reviews : PER - 1 Jun 2009
Massart Francesco, Saggese Giuseppe
Abstract excerpt
UNLABELLED: Cryptorchidism, the most common congenital abnormality in newborn boys, is a major risk factor for male infertility and testicular malignancy in adulthood. This disorder appears as an isolated form or as part of impaired male sex development or a congenital malformation syndrome. Based mainly on the laboratory studies of the rodent models, sex steroidal signaling pathways have been shown to be...
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