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Article

Fine-mapping and family-based association analyses of prostate cancer risk variants at Xp11.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2009

Lu Lingyi, Sun Jielin, Isaacs Sarah D, Wiley Kathleen E, Smith Shelly, Pruett Kristen, Zhu Yi, Zhang Zheng, Wiklund Fredrik, Grönberg Henrik, Walsh Patrick C, Chang Bao-Li, Zheng S Lilly, Isaacs William B, Xu Jianfeng

Abstract excerpt

Two single nucleotide polymorphisms (SNP; rs5945572 and rs5945619) at Xp11 were recently implicated in two genome-wide association studies of prostate cancer. Using a family-based association test for these two SNPs in 168 families with prostate cancer, we showed in this study that the risk alleles of the two reported SNPs were overtransmitted to the affected offspring (P= 0.009 for rs5945372 and P = 0.03 for...

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Identifiers

PMID: 19549809
DOI: 10.1158/1055-9965.EPI-08-1221
PMCID: PMC2795389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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