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Article

Acquired JAK-2 V617F Mutational Analysis in Pakistani Patients with Essential Thrombocythemia.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Sultan Sadia, Irfan Syed Mohammed

Abstract excerpt

BACKGROUND: Essential thrombocythemia (ET) is a clonal hemopoietic stem cell myeloproliferative neoplasm characterized by persistent thrombocytosis along with megakaryocytic hyperplasia. In the last decade following the identification of an acquired JAK2 V617F mutation, there has been acceleration in our understanding of this disease. The rational of this study was to determine the mutational profile of JAK2...

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Source

Identifiers

PMID: 26514532
DOI: 10.7314/apjcp.2015.16.16.7327

Genes

JAK2

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