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Article

S-phase cells are more sensitive to high-linear energy transfer radiation.

International journal of radiation oncology, biology, physics - 15 Jul 2009

Wang Hongyan, Liu Shuang, Zhang Piyan, Zhang Shimeng, Naidu Mamta, Wang Huichen, Wang Ya

Abstract excerpt

PURPOSE: S-phase cells are more resistant to low-linear energy transfer (LET) ionizing radiation (IR) than nonsynchronized and G(1)-phase cells, because both nonhomologous end-joining (NHEJ) and homologous recombination repair can repair DNA double-strand breaks (DSBs) in the S phase. Although it was reported 3 decades ago that S-phase cells did not show more resistance to high-LET IR than cells in other phases,...

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Source

Identifiers

PMID: 19545789
DOI: 10.1016/j.ijrobp.2008.12.089

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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