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Brain-derived neurotrophic factor Val66Met polymorphism is associated with mild cognitive impairment in elderly patients with type 2 diabetes: a case-controlled study.

Aging clinical and experimental research - 1 Jun 2021

Liu Jia, Yang Wei, Luo Hongyu, Ma Yixin, Zhao Huan, Dan Xiaojuan

Abstract excerpt

BACKGROUND: Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is reported to be associated with cognitive dysfunction, an important comorbidity factor in patients with type 2 diabetes mellitus (T2DM), especially in elderly populations, however, the underlying pathophysiological mechanisms are unclear. AIM: This study was performed to investigate the association between BDNF Val66Met polymorphism and...

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Identifiers

PMID: 32892314
DOI: 10.1007/s40520-020-01687-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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