Article
Pathophysiological underpinnings of multiple myeloma progression.
Journal of managed care pharmacy : JMCP - 1 Sept 2008
Jagannath Sundar
Abstract excerpt
BACKGROUND: Multiple myeloma (MM) is a malignant neoplasm of plasma cells that accumulate in the bone marrow. Myeloma is characterized by skeletal destruction, renal failure, hypercalcemia, and anemia. Currently, there is no cure, though recent understanding of the bone marrow microenvironment and the cytogenetics involved in MM are leading to improved and individualized treatment strategies, leading to longer...
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