Article
Antigenic basis of diversity in the gammadelta T cell co-receptor WC1 family.
Molecular immunology - 1 Aug 2009
Chen Chuang, Herzig Carolyn T A, Telfer Janice C, Baldwin Cynthia L
Abstract excerpt
WC1 co-receptors are transmembrane glycoproteins with 11 extracellular scavenger receptor cysteine rich (SRCR) domains. They are related to the CD163 family but are uniquely expressed by gammadelta T cells. We recently showed that at least 13 members comprise the WC1 gene family in cattle, a model animal species for studies of gammadelta T cell biology. Since WC1 co-receptors participate in directing functional...
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