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The scavenging capacity of DMBT1 is impaired by germline deletions

31 Mar 2017

Abstract excerpt

The Scavenger Receptor Cysteine-Rich (SRCR) proteins are an archaic group of proteins characterized by the presence of multiple SRCR domains. They are membrane-bound or secreted proteins, which are generally related to host defense systems in animals. Deleted in Malignant Brain Tumors 1 (DMBT1) is a SRCR protein which is secreted in mucosal fluids and involved in host defense by pathogen binding by its SRCR...

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PMID: 28364129
DOI: 10.1007/s00251-017-0982-x

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