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Article

Donor variation in in vitro HIV-1 susceptibility of monocyte-derived macrophages.

Virology - 1 Aug 2009

Bol Sebastiaan M, van Remmerden Yvonne, Sietzema Jantine G, Kootstra Neeltje A, Schuitemaker Hanneke, van't Wout Angélique B

Abstract excerpt

Primary human cells from different donors vary in their susceptibility to in vitro infection with HIV-1. In order to perform genetic analysis to identify host factors that affect HIV-1 susceptibility, it is important that a clear phenotype is defined. Here, we report a standardized method to study variation for in vitro HIV-1 infection in monocyte-derived macrophages (MDM) from large numbers of individuals. With...

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Source

Identifiers

PMID: 19535121
DOI: 10.1016/j.virol.2009.05.027

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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