Article
Viral phenotype and host-cell susceptibility to HIV-1 infection as risk factors for mother-to-child HIV-1 transmission.
AIDS (London, England) - 1 May 1995
Ometto L, Zanotto C, Maccabruni A, Caselli D, Truscia D, Giaquinto C, Ruga E, Chieco-Bianchi L, De Rossi A
Abstract excerpt
OBJECTIVE: To investigate the role of maternal HIV-1 isolate phenotype and a child's cell susceptibility/resistance to viral infection in mother-to-child HIV-1 transmission. PATIENTS AND METHODS: Forty-nine women were studied at the time of delivery. Primary isolates, obtained by culturing patien...
Topics
- Acquired Immunodeficiency Syndrome
- Amino Acid Sequence
- Cell Line
- Cytopathogenic Effect, Viral
- Delivery, Obstetric
- Female
- HIV Core Protein p24
- HIV-1
- Humans
- Immunity, Innate
- Infant, Newborn
- Infectious Disease Transmission, Vertical
- Leukocytes, Mononuclear
- Lymphocytes