Article
Do chemokines play a role in HIV-1 heterosexual transmission? Susceptibility to HIV infection.
Journal of biological regulators and homeostatic agents - 1 Jan 2000
D'Ubaldo C, Serraino D, Peroni M, Ippolito G
Abstract excerpt
The probability of HIV transmission depends on the infectiousness of the infected partner, the susceptibility of the healthy partner, and the biological characteristics of HIV strains. A substantial role is attributable to the individual HIV susceptibility, which is affected by immunological and genetic factors. Among genetic factors, the chemokine receptor CCR5 has been thoroughly studied. CCR5 is a co-receptor...
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