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Article

Effects of age on meiosis in budding yeast.

Developmental cell - 1 Jun 2009

Boselli Monica, Rock Jeremy, Unal Elçin, Levine Stuart S, Amon Angelika

Abstract excerpt

In humans, the frequency with which meiotic chromosome mis-segregation occurs increases with age. Whether age-dependent meiotic defects occur in other organisms is unknown. Here, we examine the effects of replicative aging on meiosis in budding yeast. We find that aged mother cells show a decreased ability to initiate the meiotic program and fail to express the meiotic inducer IME1. The few aged mother cells that...

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Share to Chromosome Segregation
Share to DNA, Ribosomal
Share to Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Meiosis

Share to Nondisjunction, Genetic

Share to Saccharomyces cerevisiae Proteins

Share to Saccharomycetales

Share to Spores, Fungal

Source

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Identifiers

PMID: 19531355
DOI: 10.1016/j.devcel.2009.05.013
PMCID: PMC2948205

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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